Do you think that Sam told Dean he was heading off to college before he told John?
How do you think Dean felt when he found out?
Do you think Dean tried to stop Sam from leaving?
If you said yes, why did he try to stop Sam?
Do you think Dean tried to get John to talk about Sam after Sam left.
Did Dean ever visit Sam at Stanford?
When was the last time (do you believe) that the boys spoke to each other (face to face) before the pilot.
How long do you think it took Sam, after he went to college, to become acclamaited to the world of normal? How long until he stopped being a hunter?
Do you ever wonder what it was like for Sam, going off to college? Do you ever wonder about the things he had to learn, simple things that we've known to do since were were young that he had to learn?
If you said yes, what sorts of things do you imagine he had to learn/was surprised to learn?